Terminology Service for NFDI4Health
Fibronectin Type III Domain-Containing Protein 5
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http://purl.obolibrary.org/obo/NCIT_C158412
Fibronectin type III domain-containing protein 5 (212 aa, ~24 kDa) is encoded by the human FNDC5 gene. This protein plays a role in the cellular response to physical reactivity. [ ]
Term info
Label
Fibronectin Type III Domain-Containing Protein 5
Synonyms
- FNDC5
- Fibronectin Type III Domain Containing Protein 5
- Fibronectin Type III Domain-Containing Protein 5
- Fibronectin Type III Repeat-Containing Protein 2
DesignNote
Following removal of the signal peptide, fibronectin type III domain-containing protein 5 is cleaved C-terminally after amino acid residue 143, which removes the transmembrane microbody targeting signal, yielding the secreted protein irisin. (UniProt)
NCI META CUI
CL937842
OMIM Number
611906
Preferred Name
Fibronectin Type III Domain-Containing Protein 5
Semantic Type
Amino Acid, Peptide, or Protein
Swiss Prot
Q8NAU1
code
C158412
Term relations
Subclass of:
- FNDC5 Gene Product
- Gene_Product_Has_Chemical_Classification some Transmembrane Protein
- Gene_Product_Has_Associated_Anatomy some Plasma Membrane
- Gene_Product_Encoded_By_Gene some FNDC5 Gene
- Gene_Product_Has_Associated_Anatomy some Membrane of the Peroxisome
- Gene_Product_Has_Structural_Domain_Or_Motif some Transmembrane Domain