Terminology Service for NFDI4Health
Ectodysplasin-A2
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http://purl.obolibrary.org/obo/NCIT_C159360
Ectodysplasin-A2 (389 aa, ~41 kDa) is encoded by the human EDA gene. This protein is involved in the positive regulation of signaling mediated by tumor necrosis factor receptor superfamily member 27. [ ]
Term info
Label
Ectodysplasin-A2
Synonyms
- ED1-A2
- EDA-A2
- EDA2
- Ectodysplasin A Isoform 3
- Ectodysplasin A2
- Ectodysplasin A2 Isoform
- Ectodysplasin-A Isoform 3
- Ectodysplasin-A2
DesignNote
Ectodysplasin-A2 is processed by furin to yield a secreted form., UniProt considers isoform 1A to be the canonical form of ectodysplasin-A. Ectodysplasin-A2 is produced by alternative splicing of the EDA transcript and is a ligand for TNFRSF27/EDA2R.
OMIM Number
300451
Preferred Name
Ectodysplasin-A2
Semantic Type
Amino Acid, Peptide, or Protein
Swiss Prot
Q92838
code
C159360
Term relations
Subclass of:
- EDA Gene Product
- Gene_Product_Has_Chemical_Classification some Transmembrane Protein
- Gene_Product_Plays_Role_In_Biological_Process some Morphogenesis
- Gene_Product_Is_Element_In_Pathway some Cytokine-Cytokine Receptor Signaling Pathway
- Gene_Product_Encoded_By_Gene some EDA Gene
- Gene_Product_Has_Associated_Anatomy some Plasma Membrane
- Gene_Product_Has_Structural_Domain_Or_Motif some Transmembrane Domain