Terminology Service for NFDI4Health
Aromatase
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http://purl.obolibrary.org/obo/NCIT_C16307
A p450-like enzyme, Aromatase catalyzes, with an NADPH-linked reductase, the oxidative aromatization of androgens to estrogens. Expressed in gonads, palcenta and brain, Aromatase and NADPH-cytochrome P450 reductase (reductase) are both highly conserved, essential components of the enzyme complex and essential for reproductive development and fertility. [ ]
Term info
Label
Aromatase
Synonyms
- Aromatase
- EC 1.14.14.1
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
Display Name
Aromatase
Legacy Concept Name
Aromatase
NCI META CUI
CL360009
Preferred Name
Aromatase
Semantic Type
Amino Acid, Peptide, or Protein, Enzyme
code
C16307
Term relations
Subclass of:
- Protein or Riboprotein Complex
- Gene_Product_Plays_Role_In_Biological_Process some Maturation
- Gene_Product_Plays_Role_In_Biological_Process some Estrogen Metabolic Process
- Gene_Product_Has_Associated_Anatomy some Endoplasmic Reticulum
- Gene_Product_Has_Biochemical_Function some Oxidoreductase
- Gene_Product_Plays_Role_In_Biological_Process some Oxidation
- Gene_Product_Plays_Role_In_Biological_Process some Drug Metabolism