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Cytochrome P450

Go to external page http://purl.obolibrary.org/obo/NCIT_C16484

A family of cytochromes that are involved in electron transport and oxidative metabolism of drugs and other bioactive molecules. When the catalytic heme is reduced the absorbance peak for this protein occurs at 450 nm. [ ]

Term info

Label

Cytochrome P450

Synonyms
  • CYP
  • CYP450
  • Cytochrome P-450
  • Cytochrome P450
  • Cytochrome P450 Enzyme
  • Cytochrome P450 Family
  • Cytochrome P450 Protein
  • Cytochrome-P450
  • P450
  • cytochrome P450 enzyme system
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

ALT DEFINITION

A group of enzymes involved in drug metabolism and found in high levels in the liver. These enzymes change many drugs, including anticancer drugs, into less toxic forms that are easier for the body to excrete.

CHEBI ID

CHEBI:38559

Display Name

Cytochrome P450

Legacy Concept Name

Cytochrome-P450

Preferred Name

Cytochrome P450

Semantic Type

Amino Acid, Peptide, or Protein, Enzyme

UMLS CUI

C0010762

code

C16484