Histone
Major protein component of chromatin. Highly conserved basic proteins, originally classified into classes based on the relative amounts of arginine and lysine in each protein. The various classes are now termed H1, H2A, H2B, H3, and H4. In chromatin, they are found in an octamer, containing two each of H2A, H2B, H3, and H4, complexed with DNA in nucleosomes. The histones in the octamer complex are also known as the core histones. The H1 class of histones, termed the linker histones, is loosely associated with the nucleosome. [ ]
Term info
Histone
- Histone
- histone
NCIT_C116977, NCIT_C142800, NCIT_C142799
A type of protein found in chromosomes. Histones bind to DNA, help give chromosomes their shape, and help control the activity of genes.
CHEBI:15358
CTRP
Histone
Histone
Histone
Amino Acid, Peptide, or Protein
C0019652
C16687
Term relations
- Structural Protein
- Gene_Product_Plays_Role_In_Biological_Process some Chromatin Structural Process
- Gene_Product_Has_Associated_Anatomy some Nucleosome
- Gene_Product_Encoded_By_Gene some Histone Gene
- Gene_Product_Has_Associated_Anatomy some Nucleus
- Gene_Product_Has_Associated_Anatomy some Chromatin
- Gene_Product_Has_Organism_Source some Human