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Protein Tyrosine Kinase

Go to external page http://purl.obolibrary.org/obo/NCIT_C17020

Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling, and can be divided into two subfamilies: receptor tyrosine kinases, that have an extracellular ligand-binding domain, a single transmembrane domain, and an intracellular tyrosine kinase domain; and nonreceptor tyrosine kinases, which are soluble, cytoplasmic kinases. (Dictionary of Cell and Molecular Biology Online) [ ]

Term info

Label

Protein Tyrosine Kinase

Synonyms
  • EC 2.7.10
  • PTK
  • Protein Tyrosine Kinase
  • Protein-Tyrosine Kinase
  • Tyrosine Kinase
  • Tyrosine Protein Kinase
  • Tyrosine-Protein Kinase
  • Tyrosine-Specific Protein Kinase
DesignNote

Formerly 2.7.1.112

Legacy Concept Name

Protein_Tyrosine_Kinase

Preferred Name

Protein Tyrosine Kinase

Semantic Type

Amino Acid, Peptide, or Protein, Enzyme

UMLS CUI

C0033681

code

C17020