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Serpin

Go to external page http://purl.obolibrary.org/obo/NCIT_C17124

Irreversible serine proteinase inhibitors that exert their action on peptidases. Serpins can be localized inside, or outside of the cell, and are found in all groups of organisms with the exception of fungi. In human plasma, serpins represent approximately 2% of the total protein present. [ ]

Term info

Label

Serpin

Synonyms
  • Serpin
DesignNote

Some members of the serpin family do not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins. These family members exhibit no serine protease inhibitory activity. (UniProt)

NCI META CUI

CL554612

Semantic Type

Amino Acid, Peptide, or Protein

code

C17124