Terminology Service for NFDI4Health
Signal Transduction
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http://purl.obolibrary.org/obo/NCIT_C17133
A cellular process that involves a chemical or mechanical stimulus and results in a specific cellular response. This process is a central feature of a broad variety of physiologic responses. [ ]
Term info
Label
Signal Transduction
Synonyms
- Cell Communication and Signaling
- Cell Signaling
- Intracellular Communication and Signaling
- Signal Transduction
- Signaling
- signal transduction
ALT DEFINITION
The process by which a cell responds to substances in its environment. The binding of a substance to a molecule on the surface of a cell causes signals to be passed from one molecule to another inside the cell. These signals can affect many functions of the cell, including cell division and cell death. Cells that have permanent changes in signal transduction molecules may develop into cancer.
Legacy Concept Name
Signal_Transduction
Preferred Name
Signal Transduction
Semantic Type
Molecular Function
UMLS CUI
C0037083
code
C17133
Term relations
Subclass of:
Related from:
Gene_Product_Plays_Role_In_Biological_Process
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- Leukemia-Associated Non-Coding IGF1R Activator RNA 1
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- MYO18A/PDGFRB Fusion Protein
- SPECC1/PDGFRB Fusion Protein
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- SRGAP3/RAF1 Fusion Protein
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- Heterotrimeric G Protein
- Suppression of Tumorigenicity 5 Protein
- Small G Protein
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- Rho GTPase-Activating Protein 29
- Epithelial Cell-Transforming Sequence 2 Oncogene-Like
- Nuclear Factor NF-kappa-B p52 Subunit
- DENN Domain-Containing Protein 3
- Arrestin Domain-Containing Protein 3
- G(i) Alpha
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- Testis-Specific Serine Kinase Substrate
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- Retinoic Acid Receptor Alpha Isoform Alpha-2
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- Sterile Alpha and TIR Motif-Containing Protein 1
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- C Peptide
- BCR/ABL1 Fusion Protein
- Mitogen-Activated Protein Kinase
- Adenylate Cyclase
- Rho Guanine Nucleotide Exchange Factor 10
- Rho Guanine Nucleotide Exchange Factor 10-Like Protein
- Protein Kinase B
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- GTPase
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Gene_Plays_Role_In_Process
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- SMAD5 Gene
- EGR3 Gene
- CD69 Gene
- CD70 Gene
- NDRG2 Gene
- CD244 Gene
- FES Gene
- MCF2 Gene
- LUNAR1 Gene
- NBEA Gene
- SH2D1B Gene
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- FAM13A Gene
- DLL4 Gene
- NEK10 Gene
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- NLK Gene
- SNCA Gene
- ARHGAP45 Gene
- Heterotrimeric G Protein Subunit Gene
- STAT4 Gene
- Phosphoinositol Kinase Family Gene
- Protein Serine/Threonine Phosphatase Gene
- Protein Tyrosine Phosphatase Gene
- RGS Family Gene
- COMMD1 Gene
- EGR1 Gene
- TFG/NTRK1 Fusion Gene
- RABEP1/PDGFRB Fusion Gene
- AKAP9/BRAF Fusion Gene
- BLNK Gene
- PPBP Gene
- PTGS1 Gene
- PTGS2 Gene
- STK3 Gene
- STK4 Gene
- NFKBIA Gene
- TPM3/NTRK1 Fusion Gene
- MAP Kinase Gene
- PTPN11 Gene
- IRAK2 Gene
- IRAK4 Gene
- ARNT2 Gene
- ADIPOR1 Gene
- ADIPOR2 Gene
- ASAH2 Gene
- CLTC/ALK Fusion Gene
- MYO18A/PDGFRB Fusion Gene
- SPECC1/PDGFRB Fusion Gene
- FGFR1OP2/FGFR1 Fusion Gene
- PRKAR1A/RET Fusion Gene
- NCOA4/RET Fusion Gene
- KIAA1549/BRAF Fusion Gene
- RNF213/ALK Fusion Gene
- TPR/MET Fusion Gene
- CARS/ALK Fusion Gene
- TXK Gene
- RAB44 Gene
- SRGAP3/RAF1 Fusion Gene
- CLEC12A Gene
- CASS4 Gene
- RAC1 Gene
- S100A1 Gene
- S100A6 Gene
- EDNRA Gene
- RAB12 Gene
- SLC38A9 Gene
- TNFAIP1 Gene
- TRAF1 Gene
- APLP1 Gene
- NPY1R Gene
- NPY2R Gene
- NPY5R Gene
- ANXA2 Gene
- NGF Gene
- OPTN Gene
- SMPD1 Gene
- DGKH Gene
- TRIB1 Gene
- RAB7A Gene
- RAB27A Gene
- HACE1 Gene
- SMPD3 Gene
- SMPD4 Gene
- IQGAP2 Gene
- RAB6B Gene
- TEAD4 Gene
- FZD1 Gene
- ACKR3 Gene
- PDGFD Gene
- MKNK2 Gene
- AKAP2 Gene
- SIAH2 Gene
- RASA1 Gene
- COPS6 Gene
- NRXN2 Gene