Terminology Service for NFDI4Health
Transcription Factor
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http://purl.obolibrary.org/obo/NCIT_C17207
Transcription factors are a diverse group of proteins that bind to DNA at specific promoter or enhancer regions. They also bind to DNA-associated proteins to initiate, stimulate, inhibit or terminate transcription. The proteins are often physically associated in a preinitiation complex and contain structural motifs. [ ]
Term info
Label
Transcription Factor
Synonyms
- Transcription Factor
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
Display Name
Transcription Factor
Legacy Concept Name
Transcription_Factor
Preferred Name
Transcription Factor
Semantic Type
Amino Acid, Peptide, or Protein
UMLS CUI
C0040648
code
C17207
Term relations
Subclass of:
- Transcription Regulatory Protein
- Gene_Product_Encoded_By_Gene some Transcription Factor Gene
- Gene_Product_Plays_Role_In_Biological_Process some DNA Binding
- Gene_Product_Has_Associated_Anatomy some Nucleus
- Gene_Product_Plays_Role_In_Biological_Process some Transcriptional Regulation
- Gene_Product_Has_Biochemical_Function some DNA Binding Protein
Related from:
Gene_Product_Has_Biochemical_Function
- Trans-Activator Protein BZLF1
- ETS Family Protein
- MAF Family Protein
- MYC Family Protein
- Nuclear Hormone Receptor Superfamily
- Gata-Binding Protein
- Swi3p
- SWI2/SNF2
- OSA
- BRAHMA
- Signal Transducer and Activator of Transcription
- SKI Oncoprotein
- Transcription Initiation Factor IIA
- Hypoxia Inducible Factor Family
- TAT Protein
- Hypoxia-Inducible Factor-1
- Core-Binding Factor
- Upstream Stimulatory Factor
- CCAAT Enhancer Binding Protein
- Early E1A Protein
- E1B Protein
- AP-1 Complex
- NF-kB
- BHLH Protein
- NF-AT
- GLI Family Protein
- Nuclear Factor-I