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Ku Protein

Go to external page http://purl.obolibrary.org/obo/NCIT_C17305

A DNA damage repair complex that, with the 470-kDa DNA-dependent protein kinase catalytic subunit (DNA-PKcs) protein, is part of the DNA-dependent protein kinase. This protein complex is involved in V(D)J recombination, nonhomologous end-joining DNA repair, and the recognition and repair of double-stranded DNA breaks. [ ]

Term info

Label

Ku Protein

Synonyms
  • ATP-Dependent DNA Helicase 2
  • ATP-Dependent DNA Helicase II
  • CTCBF
  • DNA Helicase II Complex
  • Ku
  • Ku Protein
  • La Protein
  • Lupus Autoantigen
  • Lupus Ku Autoantigen
  • TLAA
  • Thyroid-Lupus Autoantigen
DesignNote

Eukaryotic Ku is a heterodimer of two polypeptides, X-ray repair cross-complementing protein 6 (Ku70) and X-ray repair cross-complementing protein 5 (Ku80).

Legacy Concept Name

Ku_Protein

Preferred Name

Ku Protein

Semantic Type

Amino Acid, Peptide, or Protein, Enzyme

UMLS CUI

C0124761

code

C17305