Syndecan
The syndecans are a family of cell-surface heparan sulphate proteoglycans that regulate cell behavior by binding extracellular matrix molecules such as growth factors. The syndecan family has four members, of which syndecan-1 is the most studied and best characterized. In squamous cell carcinoma of the head and neck low syndecan-1 expression has been associated with unfavorable overall survival and can be used as a prognostic factor. [ ]
Term info
Syndecan
- Syndecan
- Syndecans
Syndecans
Syndecan
Amino Acid, Peptide, or Protein
C0075691
C17335
Term relations
- Protein Family
- Gene_Product_Plays_Role_In_Biological_Process some Wound Repair
- Gene_Product_Plays_Role_In_Biological_Process some Cell Adhesion Process
- Gene_Product_Plays_Role_In_Biological_Process some Signal Transduction
- Gene_Product_Has_Associated_Anatomy some Plasma Membrane
- Gene_Product_Has_Chemical_Classification some Heparan Sulfate Proteoglycan