Terminology Service for NFDI4Health
TP53 Gene
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http://purl.obolibrary.org/obo/NCIT_C17359
This gene plays a critical role in cell cycle regulation and has tumor suppressor activity. [ ]
Term info
Label
TP53 Gene
Synonyms
- P53
- TP53
- TP53 Gene
- Tumor Protein P53 (Li-Fraumeni Syndrome) Gene
Subsets
NCIT_C116977, NCIT_C142801, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
Display Name
TP53 Gene
HGNC ID
HGNC:11998
Legacy Concept Name
TP53_Gene
Maps To
TP53
OMIM Number
191170
Preferred Name
TP53 Gene
Semantic Type
Gene or Genome
UMLS CUI
C0079419
code
C17359
Term relations
Subclass of:
- Cell Cycle Gene
- Gene_Involved_In_Pathogenesis_Of_Disease some Lung Carcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Gastroesophageal Junction Adenocarcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Medullary Breast Carcinoma
- Gene_Has_Abnormality some TP53 Gene Inactivation
- Gene_Involved_In_Pathogenesis_Of_Disease some High Grade Fallopian Tube Serous Adenocarcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Cervical Carcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Schistosoma Hematobium-Related Bladder Squamous Cell Carcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Infiltrating Urothelial Carcinoma
- Gene_Plays_Role_In_Process some Aging
- Gene_Plays_Role_In_Process some Tumor Suppression
- Gene_Associated_With_Disease some Nasopharyngeal Carcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Gallbladder Adenocarcinoma
- Gene_Plays_Role_In_Process some DNA Repair
- Gene_Involved_In_Pathogenesis_Of_Disease some High Grade Ovarian Serous Adenocarcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Colorectal Carcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Oral Cavity Squamous Cell Carcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Oropharyngeal Squamous Cell Carcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Giant Cell Glioblastoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Bowenoid Papulosis
- Gene_Associated_With_Disease some Osteosarcoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Glioblastoma, IDH-Mutant
- Gene_Involved_In_Pathogenesis_Of_Disease some Anaplastic Astrocytoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Esophageal Adenocarcinoma
- Gene_Plays_Role_In_Process some Transcriptional Regulation
- Gene_Involved_In_Pathogenesis_Of_Disease some Esophageal Squamous Cell Carcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Childhood Glioblastoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Proneural Glioblastoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Serous Tubal Intraepithelial Carcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Pancreatic Intraepithelial Neoplasia-3
- Gene_Involved_In_Pathogenesis_Of_Disease some Vulvar Squamous Cell Carcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Gliosarcoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Type II Endometrial Adenocarcinoma
- Gene_Plays_Role_In_Process some Positive Regulation of Apoptosis
- Gene_Involved_In_Pathogenesis_Of_Disease some Bowen Disease of the Skin
- Gene_Involved_In_Pathogenesis_Of_Disease some Primary Peritoneal High Grade Serous Adenocarcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Laryngeal Squamous Cell Carcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Adult Glioblastoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Penile Carcinoma In Situ
- Gene_Involved_In_Pathogenesis_Of_Disease some Ampulla of Vater Adenocarcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Eccrine Porocarcinoma
- Gene_Associated_With_Disease some Breast Carcinoma
- Gene_Associated_With_Disease some Adrenal Cortex Carcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Myelodysplastic Syndrome with Gene Mutation
- Gene_Associated_With_Disease some Thyroid Gland Carcinoma
- Gene_Plays_Role_In_Process some Cell Cycle Regulation Process
- Gene_Associated_With_Disease some Hepatocellular Carcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Pancreatic Ductal Adenocarcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some Li-Fraumeni Syndrome