Terminology Service for NFDI4Health

T-Cell Receptor Alpha-Beta

Go to external page http://purl.obolibrary.org/obo/NCIT_C17433


A heterodimeric complex comprised of the highly variable T-cell receptor (TCR) alpha and beta chain proteins, which are linked by interchain disulfide bonds. This membrane bound complex is expressed on the surface of most T-lymphocytes and is involved in the recognition of peptide antigens that are presented by major histocompatibility (MHC) proteins. The alpha/beta dimer is non-covalently associated with the CD3 complex, which promotes ligand-dependent signaling. [ ]

Term info

Label

T-Cell Receptor Alpha-Beta

Synonyms
  • Alpha-Beta TCR
  • Alpha-Beta-TCR
  • Alpha/Beta TCR
  • T-Cell Receptor Alpha Beta
  • T-Cell Receptor Alpha-Beta
  • T-Cell Receptor Alpha/Beta
  • T-Cell Receptor, Alpha-Beta
  • TCR Alpha-Beta
  • TCR Alpha/Beta
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

Display Name

T-Cell Receptor Alpha-Beta

Legacy Concept Name

T-Cell_Receptor_Alpha-Beta

Preferred Name

T-Cell Receptor Alpha-Beta

Semantic Type

Amino Acid, Peptide, or Protein, Immunologic Factor, Receptor

UMLS CUI

C0085247

code

C17433