Terminology Service for NFDI4Health
AP-1 Complex
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http://purl.obolibrary.org/obo/NCIT_C17450
A dimeric complex of related bZIP JUN, FOS, MAF and ATF transcription factors that must dimerize in order to bind to AP1 recognition sites (TPA-Responsive Element, TRE) or cAMP response elements in DNA, AP-1 controls basal and inducible transcription of several genes. [ ]
Term info
Label
AP-1 Complex
Synonyms
- AP-1 Complex
- AP1
- Activator Protein 1 Complex
- Enhancer-Binding Protein AP1
- Transcription Factor AP-1 Complex
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
Display Name
AP-1 Complex
Legacy Concept Name
AP-1
OMIM Number
165160
Preferred Name
AP-1 Complex
Semantic Type
Amino Acid, Peptide, or Protein
UMLS CUI
C0085828
code
C17450
Term relations
Subclass of:
- Protein or Riboprotein Complex
- Gene_Product_Has_Structural_Domain_Or_Motif some bZIP Domain
- Gene_Product_Has_Associated_Anatomy some Nucleus
- Gene_Product_Has_Biochemical_Function some Transcription Factor
- Gene_Product_Plays_Role_In_Biological_Process some Transcriptional Regulation
- Gene_Product_Has_Organism_Source some Human