Terminology Service for NFDI4Health

E1B Protein

Go to external page http://purl.obolibrary.org/obo/NCIT_C17474


Human E1B protein (175 aa, 20 kDa) protein is encoded by the human adenovirus 2 (HadV-2) gene. This protein is transcribed by the E1B region of the HadV-2 gene, which is involved in the regulation of E1B protein levels. This protein is an inhibitor of apoptosis induced by TNF or FAS pathways, as well as p53-mediated apoptosis. Without E1B function, virus production is compromised due to the premature death of the host cell. [ ]

Term info

Label

E1B Protein

Synonyms
  • Adenovirus E1B Protein
  • E1B Protein
Legacy Concept Name

E1B_Protein

Preferred Name

E1B Protein

Semantic Type

Amino Acid, Peptide, or Protein, Immunologic Factor

UMLS CUI

C0101584

code

C17474