AP-2 Family Transcription Factor
Activator Protein 2. Originally identified as a cellular transcription factor that binds the enhancer region of SV40. It is encoded by a family of related genes, AP-2 alpha, AP-2 beta, and AP-2 gamma. AP-2 is developmentally regulated and inducible by RET. [ ]
Term info
AP-2 Family Transcription Factor
- AP-2 Family Protein
- AP-2 Family Transcription Factor
- Activator Protein-2 Family Transcription Factor
AP-2 family transcription factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. (UniProt)
AP-2_Family_Transcription_Factor
AP-2 Family Transcription Factor
Amino Acid, Peptide, or Protein
C1332097
C17545