Terminology Service for NFDI4Health
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Fusion Protein

Go to external page http://purl.obolibrary.org/obo/NCIT_C17561

A protein in which the coding region of two genes have become in-frame and co-continuous. Fusion proteins can be formed by chromosomal breakage and/or recombination and also can be experimentally created using recombinant DNA techniques. [ ]

Term info

Label

Fusion Protein

Synonyms
  • Chimera Protein
  • Chimeric Protein
  • Fusion Protein
  • fusion protein
ALT DEFINITION

A protein made from a fusion gene, which is created by joining parts of two different genes. Fusion genes may occur naturally in the body by transfer of DNA between chromosomes. For example, the BCR-ABL gene found in some types of leukemia is a fusion gene that makes the BCR-ABL fusion protein. Fusion genes and proteins can also be made in the laboratory by combining genes or parts of genes from the same or different organisms.

Legacy Concept Name

Fusion_Protein

Preferred Name

Fusion Protein

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C0162768

code

C17561