Terminology Service for NFDI4Health
Receptor Tyrosine Kinase
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http://purl.obolibrary.org/obo/NCIT_C17660
A class of membrane receptors that contain protein tyrosine kinase activity. This enzymatic activity is integral to the function of the receptor as a signal transducer; the phosphorylation event alters the functional activity of its protein substrate. [ ]
Term info
Label
Receptor Tyrosine Kinase
Synonyms
- EC 2.7.10.1
- EGF Receptor-Tyrosine Kinase Family
- RTK
- Receptor Protein-Tyrosine Kinase
- Receptor Tyrosine Kinase
- Receptor-Type Protein-Tyrosine Kinase
- Receptor-Tyrosine Kinase
- TKR
- TRK
- Transmembrane Receptor Protein Tyrosine Kinase
- Tyrosine Kinase Growth Factor Receptor
- Tyrosine Kinase Receptor
- Tyrosine Receptor Kinase
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
Display Name
Receptor Tyrosine Kinase
Legacy Concept Name
Receptor_Tyrosine_Kinase
Preferred Name
Receptor Tyrosine Kinase
Semantic Type
Amino Acid, Peptide, or Protein, Receptor, Enzyme
UMLS CUI
C0206364
code
C17660
Term relations
Subclass of:
- Protein Tyrosine Kinase
- Receptor
- Gene_Product_Plays_Role_In_Biological_Process some Tyrosine Phosphorylation
- Gene_Product_Plays_Role_In_Biological_Process some Receptor Signaling
- Gene_Product_Has_Associated_Anatomy some Plasma Membrane
- Gene_Product_Encoded_By_Gene some Receptor Tyrosine Kinase Gene
- Gene_Product_Has_Biochemical_Function some Cell Surface Receptor
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