Nuclear Receptor
Proteins that regulate transcription via interaction with chromatin and basal transcription machinery at the promoter regions of genes. Nuclear receptors are ligand-dependent transcription factors including steroids, retinoids, vitamin D, unliganded thyroid hormone, and orphan receptors (unknown ligands). Coregulators (coactivators or corepressors) are important in mediating these interactions and thereby modulate positive or negative receptor activity. [ ]
Term info
Nuclear Receptor
- Nuclear Receptor
- Receptor, Nuclear
Nuclear_Receptor
Nuclear Receptor
Amino Acid, Peptide, or Protein, Receptor
C0206588
C17671
Term relations
- Receptor and Transcription Factor and Gene_Product_Has_Chemical_Classification some Nuclear Hormone Receptor Superfamily and Gene_Product_Has_Associated_Anatomy some Nucleus and Gene_Product_Has_Associated_Anatomy some Cytoplasm and Gene_Product_Has_Structural_Domain_Or_Motif some Hormone Receptor DNA-Binding Domain and Gene_Product_Has_Biochemical_Function some Hormone Receptor and Gene_Product_Plays_Role_In_Biological_Process some Cell Differentiation Process and Gene_Product_Plays_Role_In_Biological_Process some Maturation and Gene_Product_Plays_Role_In_Biological_Process some Cell Proliferation and Gene_Product_Plays_Role_In_Biological_Process some DNA Binding and Gene_Product_Plays_Role_In_Biological_Process some Receptor Signaling and Gene_Product_Plays_Role_In_Biological_Process some Transcriptional Regulation and Gene_Product_Plays_Role_In_Biological_Process some Pattern Formation and Gene_Product_Plays_Role_In_Biological_Process some Homeostatic Process and Gene_Product_Encoded_By_Gene some Nuclear Receptor Gene