Terminology Service for NFDI4Health

Upstream Stimulatory Factor

Go to external page http://purl.obolibrary.org/obo/NCIT_C17679


The upstream stimulatory factor is a ubiquitously expressed cellular transcription factor that binds to a symmetrical DNA sequence that is found in a variety of viral and cellular promoters. Purified USF consists of 2 related polypeptides of 43 and 44 kD encoded by USF1 and USF2, respectively. USF is known to be involved in the regulation of many gene with direct and indirect roles in cancer. (from OMIM and NCI) [ ]

Term info

Label

Upstream Stimulatory Factor

Synonyms
  • USF
  • Upstream Stimulatory Factor
  • Upstream Transcription Factor
Legacy Concept Name

Upstream_Stimulatory_Factor

Preferred Name

Upstream Stimulatory Factor

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C0076925

code

C17679