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Reticulon-1

Go to external page http://purl.obolibrary.org/obo/NCIT_C17692

Reticulon-1 (776 aa, ~84 kDa) is encoded by the human RTN1 gene. This protein may play a role in neuroendocrine secretion or membrane trafficking. [ ]

Term info

Label

Reticulon-1

Synonyms
  • NSP
  • Neuroendocrine-Specific Protein
  • RTN1
  • Reticulon 1
  • Reticulon-1
DesignNote

Reticulon-1 is expressed as three isoforms (A, B, C) with unique N termini. According to UniProt, RTN1-A (NSP-A) is the canonical form; RTN1-B (NSP-B) is 356-aa and RTN1-C (NSP-C) is 208-aa. RTN1-A and RTN1-B are phosphorylated and expression of RTN1-C is correlated with neuronal differentiation. (UniProt)

Legacy Concept Name

Reticulon-1

OMIM Number

600865

Preferred Name

Reticulon-1

Semantic Type

Amino Acid, Peptide, or Protein

Swiss Prot

Q16799

UMLS CUI

C0217373

code

C17692