Terminology Service for NFDI4Health
BRCA1 Gene
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http://purl.obolibrary.org/obo/NCIT_C17965
This gene plays a role in cell cycle control, regulation of transcription and the maintenance of genomic stability. It is also involved in the inhibition of mammary cell growth. [ ]
Term info
Label
BRCA1 Gene
Synonyms
- BRCA1
- BRCA1 Gene
- BRCA1, DNA Repair Associated Gene
- Breast Cancer 1, Early Onset Gene
Subsets
NCIT_C116977, NCIT_C142801, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
Display Name
BRCA1 Gene
HGNC ID
HGNC:1100
Legacy Concept Name
BRCA1_Gene
Maps To
BRCA1
OMIM Number
113705
Preferred Name
BRCA1 Gene
Semantic Type
Gene or Genome
UMLS CUI
C0376571
code
C17965
Term relations
Subclass of:
- Homologous Recombination Repair Gene
- FA Complementation Group Gene
- Gene_Plays_Role_In_Process some Transcriptional Regulation
- Gene_Involved_In_Pathogenesis_Of_Disease some Medullary Breast Carcinoma
- Gene_Plays_Role_In_Process some Recombination Repair
- Gene_Involved_In_Pathogenesis_Of_Disease some High Grade Fallopian Tube Serous Adenocarcinoma
- Gene_Plays_Role_In_Process some DNA Binding
- Gene_Plays_Role_In_Process some DNA Recombination Process
- Gene_Involved_In_Pathogenesis_Of_Disease some Primary Peritoneal High Grade Serous Adenocarcinoma
- Gene_Plays_Role_In_Process some Chromatin Remodeling
- Gene_Involved_In_Pathogenesis_Of_Disease some High Grade Ovarian Serous Adenocarcinoma
- Gene_Plays_Role_In_Process some Double Strand Break Repair
- Gene_Involved_In_Pathogenesis_Of_Disease some Hereditary Prostate Carcinoma
- Gene_Involved_In_Pathogenesis_Of_Disease some BRCA1 Syndrome
- Gene_Has_Abnormality some BRCA1 Gene Inactivation
- Gene_Plays_Role_In_Process some Cell Cycle Checkpoint
- Gene_Involved_In_Pathogenesis_Of_Disease some Hereditary Female Breast Carcinoma