Terminology Service for NFDI4Health
FOS Family Protein
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http://purl.obolibrary.org/obo/NCIT_C18090
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. (LocusLink) [ ]
Term info
Label
FOS Family Protein
Synonyms
- FOS Family Protein
- FOS Protein
Legacy Concept Name
FOS_Family_Protein
Preferred Name
FOS Family Protein
Semantic Type
Amino Acid, Peptide, or Protein, Biologically Active Substance
UMLS CUI
C0596588
code
C18090
Term relations
Subclass of:
- Protein Family
- Gene_Product_Has_Structural_Domain_Or_Motif some bZIP Domain
- Gene_Product_Has_Associated_Anatomy some Nucleus
- Gene_Product_Plays_Role_In_Biological_Process some Transcriptional Regulation
- Gene_Product_Encoded_By_Gene some FOS Family Gene
- Gene_Product_Is_Physical_Part_Of some AP-1 Complex
- Gene_Product_Has_Biochemical_Function some DNA Binding Protein