Terminology Service for NFDI4Health
MAF Family Protein
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http://purl.obolibrary.org/obo/NCIT_C18546
Maf family proteins possess a highly conserved basic leucine zipper (bZip) domain and are subdivided into large and small Maf proteins. The Maf family proteins appear to regulate cell differentiation processes and also cellular functions as partner molecules of CNC family proteins. (from Cytogenet Cell Genet 1998;82:88-90 and CGAP) [ ]
Term info
Label
MAF Family Protein
Synonyms
- MAF Family Protein
- MAF Proteins
DesignNote
MAF proteins have been reported to be able to bind with FOS proteins to form the AP-1 transcription factor (from Nature Cell Biol. 4: E131-E136, 2002 via OMIM)
Legacy Concept Name
MAF_Family_Protein
NCI META CUI
CL414579
Preferred Name
MAF Family Protein
Semantic Type
Amino Acid, Peptide, or Protein
code
C18546
Term relations
Subclass of:
- Protein Family
- Gene_Product_Has_Structural_Domain_Or_Motif some bZIP Domain
- Gene_Product_Has_Biochemical_Function some Transcription Factor
- Gene_Product_Plays_Role_In_Biological_Process some Transcriptional Regulation
- Gene_Product_Plays_Role_In_Biological_Process some Cell Differentiation Process
- Gene_Product_Is_Physical_Part_Of some AP-1 Complex
- Gene_Product_Encoded_By_Gene some MAF Family Gene