Terminology Service for NFDI4Health
Histone Deacetylase Inhibitor
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http://purl.obolibrary.org/obo/NCIT_C1946
Any substance that inhibits histone deacetylase, an enzyme that catalyzes the removal of acetyl groups from core histones. Inhibition of histone deacetylase can result in hyperacetylation of histones, with an effect on gene expression and cell differentiation. [ ]
Term info
Label
Histone Deacetylase Inhibitor
Synonyms
- HDAC Agent
- HDAC inhibitor
- Histone Deacetylase Inhibitor
- histone deacetylase inhibitor
ALT DEFINITION
A substance that causes a chemical change that stops tumor cells from dividing. HDAC inhibitors are being studied in the treatment of cancer.
CHEBI ID
CHEBI:61115
Legacy Concept Name
Histone_Deacetylase_Inhibitor
Preferred Name
Histone Deacetylase Inhibitor
Semantic Type
Chemical Viewed Functionally
UMLS CUI
C1512474
code
C1946