Terminology Service for NFDI4Health
JSON

Recombinant Interferon Alfa-2a

Go to external page http://purl.obolibrary.org/obo/NCIT_C1952

A non-glycosylated recombinant human alpha interferon, subtype 2a, produced in the bacterium E. coli. Interferon alpha-2a binds to its specific cell-surface receptor, resulting in the transcription and translation of genes whose protein products have antiviral, antiproliferative, anticancer, and immune modulating effects. (NCI04) [ ]

Term info

Label

Recombinant Interferon Alfa-2a

Synonyms
  • Alpha 2 Interferon
  • IFN alpha-2A
  • IFN-Alpha 2
  • INTERFERON ALFA-2A
  • Interferon alfa 2a
  • Laroferon
  • Recombinant Interferon Alfa-2a
  • Recombinant Interferon Alpha-2a
  • Roceron-A
  • Roferon A
  • Roferon-A
  • rHuIFN-a 2a
Subsets

NCIT_C116978, NCIT_C128784, NCIT_C63923, NCIT_C116977, NCIT_C157711, NCIT_C157712

Accepted Therapeutic Use For

Chronic phase Philadelphia chromosome-positive chronic myelogenous leukemia; hairy cell leukemia; chronic hepatitis C; AIDs-related Kaposis sarcoma; bladder; ovarian; cervical cancer; non-Hodgkins lymphoma; renal cell carcinoma; melanoma.

CAS Registry

76543-88-9

Display Name

Recombinant Interferon Alfa-2a

FDA UNII Code

47RRR83SK7

Legacy Concept Name

Interferon_Alpha-2a

NSC Code

367982

Preferred Name

Recombinant Interferon Alfa-2a

Semantic Type

Pharmacologic Substance, Amino Acid, Peptide, or Protein

UMLS CUI

C0021734

code

C1952