Tfg3 (TFIIF) is a general stimulatory transcription initiation factor that binds to RNA Polymerase II decreasing its affinity for non-specific DNA. Tfg3 is also a component of the mediator complex and is important for cellular morphogenesis and actin cytoskeletal function. Tfg3 is composed of three subunits and is similar to human ENL and AF-9 proteins. (from SWISS-PROT P35189 and NCI) [ ]