Terminology Service for NFDI4Health

RUNX1/RUNX1T1 Fusion Protein

Go to external page http://purl.obolibrary.org/obo/NCIT_C19892


A fusion protein (752 aa, ~83 kDa) encoded by the RUNX1/RUNX1T1 fusion gene. This protein is comprised of the N-terminal runt domain of the runt-related transcription factor 1 protein fused to the 577 C-terminal residues of protein CBFA2T1. [ ]

Term info

Label

RUNX1/RUNX1T1 Fusion Protein

Synonyms
  • AML-1/ETO
  • AML1-ETO Fusion Protein
  • AML1-MTG8 Fusion Protein
  • AML1/MTG8 Fusion Protein
  • Acute Myeloid Leukemia-1/Eight-Twenty-One Protein
  • RUNX1-RUNX1T1 Fusion Protein
  • RUNX1/RUNX1T1 Fusion Protein
  • Runt-Related Transcription Factor 1/Protein CBFA2T1 Fusion Protein
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

Display Name

RUNX1/RUNX1T1 Fusion Protein

Legacy Concept Name

AML1-ETO_Chimeric_Protein

Preferred Name

RUNX1/RUNX1T1 Fusion Protein

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C18579, http://purl.obolibrary.org/obo/NCIT_C28570

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C0665119

code

C19892