Terminology Service for NFDI4Health
Nuclear Factor-I
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http://purl.obolibrary.org/obo/NCIT_C20186
A family of proteins that contain 1 DWA/MH1 domain and bind 5'-TTGGCNNNNNGCCAA-3' DNA palindromes in viral and cellular promoters as homodimeric factors capable of activating transcription and replication. [ ]
Term info
Label
Nuclear Factor-I
Synonyms
- CCAAT-Binding Transcription Factor
- CCAAT-Box Binding Transcription Factor
- CTF
- NF-I
- NF-I Protein
- NFI
- Nuclear Factor I
- Nuclear Factor-I
- Nuclear Factor-I Family
- TGGCA-Binding Protein
Legacy Concept Name
NF-I
Preferred Name
Nuclear Factor-I
Semantic Type
Amino Acid, Peptide, or Protein
UMLS CUI
C0069116
code
C20186
Term relations
Subclass of:
- Protein Family
- Gene_Product_Plays_Role_In_Biological_Process some DNA Replication
- Gene_Product_Plays_Role_In_Biological_Process some DNA Binding
- Gene_Product_Has_Associated_Anatomy some Nucleus
- Gene_Product_Has_Biochemical_Function some Transcription Factor
- Gene_Product_Plays_Role_In_Biological_Process some Transcriptional Regulation
- Gene_Product_Has_Organism_Source some Human