Terminology Service for NFDI4Health

Telomere Maintenance Gene

Go to external page http://purl.obolibrary.org/obo/NCIT_C20338


Telomere Maintenance Genes encode specialized proteins bound to telomeric DNA repeats and directly involved in maintaining/protecting chromosome telomere ends to prevent a damage response that halts cell proliferation. Telomerase, which lengthens telomeric DNA by RNA-templated addition of repeated DNA sequences, is regulated by proteins that bind to the telomeric DNA repeats and to additional proteins to assemble a higher-order telomeric complex. (NCI) [ ]

Term info

Label

Telomere Maintenance Gene

Synonyms
  • Telomere Maintenance Gene
Legacy Concept Name

Telomere_Maintenance_Gene

Preferred Name

Telomere Maintenance Gene

Semantic Type

Gene or Genome

UMLS CUI

C1336700

code

C20338