Terminology Service for NFDI4Health
Transforming Growth Factor-Beta Superfamily
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http://purl.obolibrary.org/obo/NCIT_C20455
A family of structurally-related cytokines that bind to their cognate serine/threonine kinase receptors as homodimers or heterodimers linked by a single disulfide bond. These proteins play a role in embryonic development, hematopoiesis, tissue repair and extracellular matrix remodeling. [ ]
Term info
Label
Transforming Growth Factor-Beta Superfamily
Synonyms
- Bone-Derived Transforming Growth Factor
- Milk Growth Factor
- TGF B
- TGF-B
- TGF-Beta
- Transforming Growth Factor-Beta
- Transforming Growth Factor-Beta Superfamily
- Tumor Growth Factor B
- Tumor Growth Factor Beta
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
Display Name
Transforming Growth Factor-Beta Superfamily
Legacy Concept Name
Transforming_Growth_Factor-Beta
Preferred Name
Transforming Growth Factor-Beta Superfamily
Semantic Type
Amino Acid, Peptide, or Protein
UMLS CUI
C0040690
code
C20455
Term relations
Subclass of:
- Growth Factor
- Gene_Product_Has_Biochemical_Function some Transforming Growth Factor
- Gene_Product_Plays_Role_In_Biological_Process some Intercellular Communication Process
- Gene_Product_Plays_Role_In_Biological_Process some Receptor Signaling
- Gene_Product_Encoded_By_Gene some Transforming Growth Factor-Beta Family Gene
- Gene_Product_Plays_Role_In_Biological_Process some Receptor Binding
- Gene_Product_Plays_Role_In_Biological_Process some Cell Differentiation Process
- Gene_Product_Plays_Role_In_Biological_Process some Cell Proliferation Regulatory Process
- Gene_Product_Is_Biomarker_Type some Disease Marker
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