Terminology Service for NFDI4Health

Transcription Coactivator Gene

Go to external page http://purl.obolibrary.org/obo/NCIT_C20673


RNA polymerase II transcription of Class II genes involves the TFIID transcription complex comprised of general factors, including TBP, TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIG/J, and TFIIH, as well as gene-specific factors that include TAFs, which interact with regulatory protein activation domains to enhance transcription. A second group of cofactors includes PC1, PC2, and PC3, which have a strong positive influence on transcription. The combined action of general and gene-specific regulators encoded by Transcription Coactivator Genes enhances gene expression. (NCI) [ ]

Term info

Label

Transcription Coactivator Gene

Synonyms
  • Transcription Coactivator Gene
Gene Encodes Product

Transcription Coactivator

Legacy Concept Name

Transcription_Coactivator_Gene

Preferred Name

Transcription Coactivator Gene

Semantic Type

Gene or Genome

UMLS CUI

C1336777

code

C20673