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MHC Class II Protein

Go to external page http://purl.obolibrary.org/obo/NCIT_C20705

MHC Class-II Proteins are non-covalently linked polymorphic alpha/beta transmembrane glycoproteins. The immunological function of MHC Class-II proteins is to bind and present antigenic peptides on the surfaces of cells for recognition by the antigen-specific T cell receptors of lymphocytes. These proteins plays an important role in the mediation of immune response. [ ]

Term info

Label

MHC Class II Protein

Synonyms
  • Class II MHC Protein
  • HLA
  • Histocompatibility Antigen, Class II
  • Human Leukocyte Antigen
  • MHC Class II Molecule
  • MHC Class II Protein
  • Major Histocompatibility Complex Class II
  • human leukocyte antigen
  • human lymphocyte antigen
ALT DEFINITION

One of a group of proteins found on the surface of white blood cells and other cells that play an important part in the body's immune response to foreign substances. These antigens vary from person to person, and human leukocyte antigen tests are done before organ transplantation to find out if tissues match between a donor and a recipient.

Legacy Concept Name

MHC_Class-II_Protein

Preferred Name

MHC Class II Protein

Semantic Type

Amino Acid, Peptide, or Protein, Immunologic Factor

UMLS CUI

C0019630

code

C20705