Terminology Service for NFDI4Health
Cadherin-13
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http://purl.obolibrary.org/obo/NCIT_C21022
Cadherin-13 (713 aa, ~78 kDa) is encoded by the human CDH13 gene. This protein plays a role in cell-cell adhesion. [ ]
Term info
Label
Cadherin-13
Synonyms
- CDH13
- Cadherin 13
- Cadherin-13
- H-Cadherin
- Heart Cadherin
- P105
- T-Cad
- T-Cadherin
- Truncated-Cadherin
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
DesignNote
Encoded by human CDH13 Gene (CDH Family), 713-amino acid 78 kD (precursor) putative tumor suppressor Cadherin 13 is a Ca(2+)-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats. H-Cadherin lacks the conserved cytoplasmic region and is attached to the membrane by a GPI-anchor, unlike typical cadherins. Highest expression is observed in the heart. CNS expression is higher in adult than in fetus. A putative mediator of cell interactions, this cadherin may inhibit neural cell growth.
Display Name
Cadherin-13
Legacy Concept Name
H-Cadherin
OMIM Number
601364
Preferred Name
Cadherin-13
Semantic Type
Amino Acid, Peptide, or Protein
Swiss Prot
P55290
UMLS CUI
C1570804
code
C21022
Term relations
Equivalent to:
- Cadherin and Gene_Product_Has_Chemical_Classification some Glycoprotein and Gene_Product_Has_Associated_Anatomy some Plasma Membrane and Gene_Product_Expressed_In_Tissue some Central Nervous System and Gene_Product_Expressed_In_Tissue some Heart and Gene_Product_Has_Structural_Domain_Or_Motif some Cadherin Domain and Gene_Product_Plays_Role_In_Biological_Process some Cell-Matrix Adhesion Process and Gene_Product_Encoded_By_Gene some CDH13 Gene