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Transforming Acidic Coiled-Coil-Containing Protein 1

Go to external page http://purl.obolibrary.org/obo/NCIT_C21225

Transforming acidic coiled-coil-containing protein 1 (805 aa, ~88 kDa) is encoded by the human TACC1 gene. This protein may be involved in cell division and histogenesis. [ ]

Term info

Label

Transforming Acidic Coiled-Coil-Containing Protein 1

Synonyms
  • Acidic Coiled-Coil Protein 1
  • Gastric Cancer Antigen Ga55
  • TACC1
  • TACC1 Protein
  • Taxin 1
  • Transforming Acidic Coiled-Coil-Containing Protein 1
DesignNote

Transforming acidic coiled-coil-containing protein 1 is rich in serine, proline, and acidic residues, with a 20-amino acid N-terminus rich in tryptophan, and contains two nuclear localization signals but no DNA- or RNA-binding domains. A 200-residue C-terminus with extensive alpha-helical segments is expected to adopt a coiled-coil structure. This nuclear protein is concentrated at centrosomes and interacts with microtubules and tubulin. (Swiss-Prot, OMIMI)

Legacy Concept Name

Transforming_Acidic_Coiled-Coil_Containing_Protein-1

OMIM Number

605301

Preferred Name

Transforming Acidic Coiled-Coil-Containing Protein 1

Semantic Type

Amino Acid, Peptide, or Protein

Swiss Prot

O75410

UMLS CUI

C0907959

code

C21225