Terminology Service for NFDI4Health
Inhibin
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http://purl.obolibrary.org/obo/NCIT_C2276
Inhibins are peptide hormones, secreted by the follicular cells of the ovary and by the testis, that negatively regulate the synthesis and secretion of follicle stimulating hormone from the anterior pituitary. The detection of serum inhibins has been implicated in association with reproductive disorders, including infertility and ovarian cancers. [ ]
Term info
Label
Inhibin
Synonyms
- Folliculostatin
- Inhibin
- Inhibin Hormone
CAS Registry
57285-09-3
DesignNote
Both inhibin A and inhibin B are heterodimers consisting of an alpha subunit and a beta A or beta B subunit linked by disulphide bonds. Both inhibins function as negative regulators for FSH synthesis and secretion. Furthermore, serum concentrations of inhibins transit from inhibin B to inhibin A dominance during menstrual cycle.
Legacy Concept Name
Inhibin
Preferred Name
Inhibin
Semantic Type
Hormone, Amino Acid, Peptide, or Protein
UMLS CUI
C0021463
code
C2276
Term relations
Subclass of:
- Protein or Riboprotein Complex
- Gene_Product_Plays_Role_In_Biological_Process some Protein Secretion
- Gene_Product_Has_Biochemical_Function some Peptide Hormone
- Gene_Product_Plays_Role_In_Biological_Process some Intercellular Communication Process
- Gene_Product_Plays_Role_In_Biological_Process some Reproduction