Terminology Service for NFDI4Health
Monoclonal Antibody A27.15
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http://purl.obolibrary.org/obo/NCIT_C2447
A murine IgG1 monoclonal antibody directed against the human transferrin (Tf) receptor. Monoclonal antibody A27.15 binds to the Tf receptor, blocking the binding of transferrin to the receptor and resulting in decreased tumor cell growth. (NCI04) [ ]
Term info
Label
Monoclonal Antibody A27.15
Synonyms
- A27.15
- ANTI-TRANSFERRIN MOAB 27.15
- MoAb A27.15
- Monoclonal Antibody A27.15
Subsets
NCIT_C128784, NCIT_C157711, NCIT_C157712
Legacy Concept Name
Monoclonal_Antibody_A27_15
NSC Code
644261
PDQ Open Trial Search ID
42834
Preferred Name
Monoclonal Antibody A27.15
Semantic Type
Amino Acid, Peptide, or Protein, Immunologic Factor
UMLS CUI
C0677772
code
C2447
Term relations
Subclass of:
- Monoclonal Antibody
- Antineoplastic Antibody
- Chemical_Or_Drug_Has_Physiologic_Effect some Inhibition of Cell Proliferation
- Chemical_Or_Drug_Affects_Gene_Product some Transferrin Receptor
- Chemical_Or_Drug_Has_Mechanism_Of_Action some Negative Regulation of Receptor Activation
- Chemical_Or_Drug_Has_Mechanism_Of_Action some Antigen Binding
- Chemical_Or_Drug_Has_Physiologic_Effect some Iron Uptake Inhibition