Terminology Service for NFDI4Health
Monoclonal Antibody HeFi-1
Go to external page
http://purl.obolibrary.org/obo/NCIT_C2505
A murine monoclonal antibody with potential antineoplastic activity. Monoclonal antibody HeFi-1 binds to CD30, a cell surface antigen found on mitogen-activated B-cells and T-cells, and Reed-Sternberg cells. Monoclonal antibody HeFi-1 has been shown to arrest tumor growth and prevent metastasis in animal models. (NCI04) [ ]
Term info
Label
Monoclonal Antibody HeFi-1
Synonyms
- HeFi-1
- MoAb HeFi-1
- Monoclonal Antibody HeFi-1
Subsets
NCIT_C128784, NCIT_C157711, NCIT_C157712
Has Target
http://purl.obolibrary.org/obo/NCIT_C38906
Legacy Concept Name
Monoclonal_Antibody_HeFi-1
NSC Code
603573
PDQ Open Trial Search ID
43332
Preferred Name
Monoclonal Antibody HeFi-1
Semantic Type
Amino Acid, Peptide, or Protein, Immunologic Factor
UMLS CUI
C0796480
code
C2505
Term relations
Subclass of:
- Monoclonal Antibody
- Antineoplastic Antibody
- Chemical_Or_Drug_Affects_Gene_Product some Tumor Necrosis Factor Receptor Superfamily Member 8
- Chemical_Or_Drug_Affects_Cell_Type_Or_Tissue some T-Lymphocyte
- Chemical_Or_Drug_Affects_Abnormal_Cell some Reed-Sternberg Cell
- Chemical_Or_Drug_Has_Physiologic_Effect some Inhibition of Cell Proliferation
- Chemical_Or_Drug_Has_Mechanism_Of_Action some Antigen Binding
- Chemical_Or_Drug_Has_Physiologic_Effect some Metastasis Suppression
- Chemical_Or_Drug_Affects_Cell_Type_Or_Tissue some B-Lymphocyte