Terminology Service for NFDI4Health

Carcinoembryonic Antigen

Go to external page http://purl.obolibrary.org/obo/NCIT_C25159


A cancer-specific antigen associated with both tumors and the developing fetus. The main use of this antigen is as a tumor marker, especially with respect to intestinal cancers. Production of the antigen ceases shortly before birth, but may reappear in people who develop certain types of cancer. [ ]

Term info

Label

Carcinoembryonic Antigen

Synonyms
  • CEA
  • CEA Family Protein
  • Carcinoembryonic Antigen
  • Carcinoembryonic Antigen Family Protein
  • carcinoembryonic antigen
ALT DEFINITION

A substance that is sometimes found in an increased amount in the blood of people who have certain cancers, other diseases, or who smoke. It is used as a tumor marker for colorectal cancer.

DesignNote

The term carcinoembryonic antigen (CEA) may refer to the CEA protein family but it is sometimes used to refer to CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5) alone., Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. (OMIM)

Legacy Concept Name

Carcinoembryonic_Antigen

Preferred Name

Carcinoembryonic Antigen

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C0007082

code

C25159