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Lactate Dehydrogenase

Go to external page http://purl.obolibrary.org/obo/NCIT_C25184

A family of homotetrameric cytoplasmic enzymes involved in the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. In vertebrates, genes for three different subunits (LDH-A, LDH-B and LDH-C) exist. [ ]

Term info

Label

Lactate Dehydrogenase

Synonyms
  • EC 1.1.1.27
  • L-(+)-Lactate Dehydrogenase
  • L-Lactic Acid Dehydrogenase
  • LDH
  • Lactate Dehydrogenase
  • Lactic Acid Dehydrogenase
  • NAD-Lactate Dehydrogenase
  • lactate dehydrogenase
  • lactic acid dehydrogenase
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

ALT DEFINITION

One of a group of enzymes found in the blood and other body tissues and involved in energy production in cells. An increased amount of lactate dehydrogenase in the blood may be a sign of tissue damage and some types of cancer or other diseases.

Display Name

Lactate Dehydrogenase

Legacy Concept Name

Lactate_Dehydrogenase

Preferred Name

Lactate Dehydrogenase

Semantic Type

Amino Acid, Peptide, or Protein, Enzyme

UMLS CUI

C0022917

code

C25184