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SGOT (AST)

Go to external page http://purl.obolibrary.org/obo/NCIT_C25202

Activity measured as a test of liver function, 46/47-kDa homodimeric human Aspartate Aminotransferases (Class-I Pyridoxal-Phosphate-Dependent Aminotransferase Family) are pyridoxal phosphate-dependent enzymes involved in amino acid metabolism and in the urea and tricarboxylic acid cycles. (NCI) [ ]

Term info

Label

SGOT (AST)

Synonyms
  • AST
  • SGOT
  • SGOT (AST)
  • aspartate transaminase
  • serum glutamic-oxaloacetic transaminase
ALT DEFINITION

An enzyme found in the liver, heart, and other tissues. A high level of serum glutamic-oxaloacetic transaminase released into the blood may be a sign of liver or heart damage, cancer, or other diseases.

DesignNote

Urea Cycle, Tricarboxylic Acid Cycle, Transamination

Legacy Concept Name

SGOT-AST_Protein

Preferred Name

SGOT (AST)

Semantic Type

Amino Acid, Peptide, or Protein, Enzyme

UMLS CUI

C0242192

code

C25202