Terminology Service for NFDI4Health

Chaperone Gene

Go to external page http://purl.obolibrary.org/obo/NCIT_C25802


Genes that encode cytoplasmic proteins of both prokaryotes and eukaryotes that bind to nascent or unfolded polypeptides and ensure correct folding or transport. Chaperone proteins do not covalently bind to their targets and do not form part of the finished product. Heat-shock proteins are an important sub set of chaperones. Three major families are recognised, the chaperonins (groEL and hsp60), the hsp70 family and the hsp90 family. Outside these major families are other proteins with similar functions including nucleoplasmin, secB and T-cell receptor associated protein. [ ]

Term info

Label

Chaperone Gene

Synonyms
  • Chaperone Gene
Legacy Concept Name

Chaperone_Gene

Preferred Name

Chaperone Gene

Semantic Type

Gene or Genome

UMLS CUI

C1332924

code

C25802