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Cerebellar-Degeneration-Related Antigen 1

Go to external page http://purl.obolibrary.org/obo/NCIT_C25897

Cerebellar degeneration-related antigen 1 (262 aa, ~31 kDa) is encoded by the human CDR1 gene. This protein is involved in autoimmune diseases. [ ]

Term info

Label

Cerebellar-Degeneration-Related Antigen 1

Synonyms
  • CDR
  • CDR1
  • CDR1 Protein
  • CDR34
  • CDR62A
  • Cerebellar Degeneration-Related Autoantigen 1
  • Cerebellar Degeneration-Related Autoantigen, 34-kD
  • Cerebellar Degeneration-Related Protein (34kD)
  • Cerebellar Degeneration-Related Protein 1
  • Cerebellar Degeneration-Related Protein 1, 34kDa
  • Cerebellar Degeneration-Related Protein-1 (34kD)
  • Cerebellar-Degeneration-Related Antigen 1
DesignNote

A peptide derived from cerebellar degeneration-related antigen 1, Edratide, is used to treat lupus., Cerebellar-Degeneration-Related Antigen 1, encoded by the human CDR1 gene, is one of the target molecules recognized by autoantibodies directed against neuronal proteins in patients with paraneoplastic cerebellar degeneration, which occurs in association with small cell carcinoma of the lung, neoplasms of the breast and ovary, and Hodgkin disease. This protein contains tandem hexapeptide repeats and is expressed in brain, predominantly in normal neuroectodermal tissues and in certain malignant tumors. (From LocusLink, Swiss-Prot and NCI)

Legacy Concept Name

Cerebellar-Degeneration-Related_Antigen-1

OMIM Number

302650

Preferred Name

Cerebellar-Degeneration-Related Antigen 1

Semantic Type

Amino Acid, Peptide, or Protein

Swiss Prot

P51861

UMLS CUI

C1437277

code

C25897