Terminology Service for NFDI4Health
Suppressor of Cytokine Signaling Family Protein
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http://purl.obolibrary.org/obo/NCIT_C25978
A family of proteins that function downstream of cytokine receptors to modulate signal transduction. Members of the family contain SH2 and SOCS BOX domains. [ ]
Term info
Label
Suppressor of Cytokine Signaling Family Protein
Synonyms
- CIS Family Protein
- Cytokine-Induced STAT Inhibitor Family Protein
- SOCS Family Protein
- SOCS Protein
- SSI Family Protein
- STAT-Induced STAT Inhibitor Family Protein
- Suppressor of Cytokine Signaling Family Protein
DesignNote
SOCS proteins are implicated in ubiquitin-dependent protein degradation. Members of this family of proteins are involved in the regulation of cell growth and survival, placental development, hematopoiesis, and T-cell response to allergens.
Legacy Concept Name
Suppressor_of_Cytokine_Signaling_Family_Protein
Preferred Name
Suppressor of Cytokine Signaling Family Protein
Semantic Type
Amino Acid, Peptide, or Protein
UMLS CUI
C1564682
code
C25978