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Ubiquitin-Activating Enzyme Gene

Go to external page http://purl.obolibrary.org/obo/NCIT_C26066

Genes encoding enzymes that catalyze the first step in the ubiquitination reaction via the ligation of the C-terminal lysine of ubiquitin to the E1 enzyme in an ATP-dependent reaction. [ ]

Term info

Label

Ubiquitin-Activating Enzyme Gene

Synonyms
  • E1 Ubiquitin-Activating Enzyme Gene
  • Ubiquitin-Activating Enzyme Gene
DesignNote

The IUBMB has recategorized E2 ubiquitin-conjugating enzymes and E3 ubiquitin-protein ligases as transferases (EC 2). Thus, E1, E2 and E3 enzymes may be considered part of a ubiquitin ligase complex, but only E1 enzymes are categorized as ligases (EC 6).

Legacy Concept Name

Ubiquitin_Ligase_Gene

NCI META CUI

CL520265

Preferred Name

Ubiquitin-Activating Enzyme Gene

Semantic Type

Gene or Genome

code

C26066