Terminology Service for NFDI4Health
Drug Metabolism
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http://purl.obolibrary.org/obo/NCIT_C26633
A series of chemical modifications of a drug compound by enzymatic activity that make the substrate (drug) more water soluble to allow its clearance from the body. Drug metabolism occurs in two phases: Phase I (biotransformation) involves oxidation, hydroxylation reduction, and hydrolysis. Phase II (conjugation) involves synthesis and conjugation. [ ]
Term info
Label
Drug Metabolism
Synonyms
- Drug Metabolism
Legacy Concept Name
Drug_Metabolism
Preferred Name
Drug Metabolism
Semantic Type
Molecular Function
UMLS CUI
C0683140
code
C26633
Term relations
Subclass of:
- Xenobiotic Metabolism
- Biological_Process_Has_Initiator_Chemical_Or_Drug some Pharmacologic Substance
Related from:
Allele_Plays_Altered_Role_In_Process
- CYP2D6*4 Allele
- CYP2C9*3 Allele
- CYP2C9*5 Allele
- CYP2D6*10 Allele
- CYP2C9*2 Allele
- CYP2D6*17 Allele
- CYP2D6*2N Allele
- CYP2D6*5 Allele
- CYP2D6*6 Allele
- CYP2D6*8 Allele
- CYP2C19*3 Allele
- CYP2C19*2 Allele
- CYP2C19*4 Allele
- CYP2C19*5 Allele
- CYP2C19*6 Allele
- CYP2D6*18 Allele
- CYP2D6*19 Allele
- CYP2D6*20 Allele
- CYP2D6*40 Allele
- CYP2D6*41 Allele
- CYP2D6*42 Allele
- CYP2C9*18 Allele
- CYP2C9*16 Allele
- CYP2C9*12 Allele
- CYP3A5*8 Allele
- CYP3A5*6 Allele
- CYP3A5*3 Allele
- CYP3A7*2 Allele
- CYP3A4*18 Allele
- CYP3A4*17 Allele
- CYP3A5*10 Allele
- CYP3A5*9 Allele
- CYP2C19*7 Allele
- CYP2C19*10 Allele
- CYP2C19*9 Allele
- CYP2C19*8 Allele
- CYP2C9*11 Allele
- CYP2C9*8 Allele
- CYP2C9*6 Allele
- CYP2C19*12 Allele
- CYP1A2*11 Allele
- CYP2D6*12 Allele
- CYP2D6*11 Allele
- CYP2D6*9 Allele
- CYP2D6*7 Allele
- CYP2D6*16 Allele
- CYP2D6*15 Allele
- CYP2D6*14 Allele
- CYP2D6*13 Allele
- CYP2D6*3 Allele
- CYP2E1*2 Allele
- CYP2E1*1 Allele
- CYP2C8*5 Allele
- CYP2C8*3 Allele
- CYP1A2*7 Allele
- CYP1A2*1 Allele
- CYP2C8*8 Allele
- CYP2C8*7 Allele
- CYP2C8*2 Allele
- CYP2D6*44 Allele
- CYP2D6*38 Allele
- CYP2D6*36 Allele
- CYP2D6*35X2 Allele
- CYP2D6*21 Allele