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Recombinant Fowlpox-TRICOM Vaccine

Go to external page http://purl.obolibrary.org/obo/NCIT_C2667

A vaccine comprised of a recombinant fowlpox virus vector encoding a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM), which may enhance antigen presentation and activate cytotoxic T-cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells. (NCI04) [ ]

Term info

Label

Recombinant Fowlpox-TRICOM Vaccine

Synonyms
  • Recombinant Fowlpox-TRICOM
  • Recombinant Fowlpox-TRICOM Vaccine
  • rF-TRICOM
  • rF-TRICOM (B7.1.iCAM1-LFA3-Fowlpox)
  • recombinant fowlpox-TRICOM vaccine
Subsets

NCIT_C116978, NCIT_C128784, NCIT_C116977

ALT DEFINITION

A cancer vaccine made with a form of a chicken virus that does not cause disease in humans. It is being studied in the treatment of some types of cancer. The virus is changed in the laboratory to make human proteins that may help immune cells in the body kill tumor cells.

Display Name

Recombinant Fowlpox-TRICOM Vaccine

Legacy Concept Name

Fowlpox-TRICOM_Vaccine

NSC Code

710658

Preferred Name

Recombinant Fowlpox-TRICOM Vaccine

Semantic Type

Virus, Pharmacologic Substance

UMLS CUI

C1134570

code

C2667