Terminology Service for NFDI4Health
Recombinant Vaccinia-TRICOM Vaccine
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http://purl.obolibrary.org/obo/NCIT_C2685
A vaccine consisting of recombinant vaccinia virus encoding a TRIad of COstimulatory Molecules (B7-1, ICAM-1, and LFA-3; also called TRICOM). Vaccination with recombinant vaccinia-TRICOM vaccine stimulates the host immune system to mount a non-specific T-cell response. With the addition of a tumor-associated antigen peptide, this vaccine may enhance a tumor-specific immune response. [ ]
Term info
Label
Recombinant Vaccinia-TRICOM Vaccine
Synonyms
- Recombinant Vaccinia-TRICOM Vaccine
- Vaccinia-TRICOM
- rV-TRICOM
- recombinant vaccinia-TRICOM vaccine
- vaccinia-TRICOM vaccine
Subsets
NCIT_C116978, NCIT_C128784, NCIT_C116977
ALT DEFINITION
A cancer vaccine made with a form of a vaccinia virus that does not cause disease in humans. It is being studied in the treatment of some types of cancer. The virus is changed in the laboratory to make human proteins that may help immune cells in the body kill tumor cells.
Contributing Source
CTRP
Display Name
Recombinant Vaccinia-TRICOM Vaccine
Legacy Concept Name
Vaccinia-TRICOM_Vaccine
NSC Code
708039
PDQ Open Trial Search ID
38659
Preferred Name
Recombinant Vaccinia-TRICOM Vaccine
Semantic Type
Virus, Pharmacologic Substance
UMLS CUI
C1099097
code
C2685