Terminology Service for NFDI4Health

Vitaxin-2

Go to external page http://purl.obolibrary.org/obo/NCIT_C2734


A modified version of Vitaxin, a humanized monoclonal IgG1 antibody to alpha(v)beta(3)integrin. Exhibiting improved affinity to alpha(v)beta(3)integrin compared to first-generation Vitaxin, Vitaxin-2 blocks the binding of ligands, such as vitronectin, to alpha(v)beta(3) integrin, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. (NCI04) [ ]

Term info

Label

Vitaxin-2

Synonyms
  • Monoclonal Antibody Anti-Avb3 Integrin
  • Vitaxin 2
  • Vitaxin-2
Preferred Name

Vitaxin-2

Semantic Type

Pharmacologic Substance, Amino Acid, Peptide, or Protein

UMLS CUI

C1523981

code

C2734