Terminology Service for NFDI4Health
VHL14 Peptide
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http://purl.obolibrary.org/obo/NCIT_C2741
A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. VHL14 peptide is a point mutation variant of the VHL protein; the mutation is in amino acid position 166. It might be used to elicit or boost cellular immunity to cancers that expressing the von Hippel-Lindau mutation. (NCI04) [ ]
Term info
Label
VHL14 Peptide
Synonyms
- (V166A) VHL14
- Berzofsky VHL Peptide
- Berzofsky VHL Peptide (CLQVARSLVK)
- V166A
- VHL14
- VHL14 Peptide
Legacy Concept Name
VHL14
NSC Code
721380
Preferred Name
VHL14 Peptide
Semantic Type
Pharmacologic Substance, Amino Acid, Peptide, or Protein
UMLS CUI
C1519881
code
C2741
Term relations
Subclass of:
- Von Hippel-Lindau Peptide Vaccine
- Chemical_Or_Drug_Has_Physiologic_Effect some T-Cell Activation
- Chemical_Or_Drug_Affects_Cell_Type_Or_Tissue some Cytotoxic T-Lymphocyte
- Chemical_Or_Drug_Has_Mechanism_Of_Action some Antigen Sensitization
- Chemical_Or_Drug_Has_Physiologic_Effect some Immunopotentiation